Palladium-catalyzed direct C-H arylation of cyclic enaminones with aryl iodides.
نویسندگان
چکیده
A ligand-free method for the Pd-catalyzed direct arylation of cyclic enaminones using aryl iodides was developed. This method can be applied to a wide range of cyclic enaminones and aryl iodides with excellent C5-regioselectivity. Using widely available aryl iodides, the generality of this transformation provides easy access to a variety of 3-arylpiperidine structural motifs.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 78 12 شماره
صفحات -
تاریخ انتشار 2013